3′,4′-Didehydro-3′-deoxyguanosine triphosphate– CAS 2499590-39-3


3′,4′-Didehydro-3′-deoxyguanosine triphosphate – CAS 2499590-39-3 is synthesized by Santiago Lab (Prague, Czech Republic)

Purity (LC-MS)

min 95%

Package contents

3′,4′-Didehydro-3′-deoxyguanosine triphosphate triethylammonium salt

This compound is for research use only. We do not sell to patients.
1 mg

In stock

5 mg

In stock


3′,4′-Didehydro-3′-deoxyguanosine triphosphate– CAS 2499590-39-3


CAS: 2499590-39-3, 2787607-91-2 (Et3NH+ salt)

IUPAC Name: ((4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-hydroxy-4,5-dihydrofuran-2-yl)methyl tetrahydrogen triphosphate

Other names: DdhG-TP, Ddh-G triphosphate, 3′,4′-Didehydro-3′-deoxyguanosine triphosphate

Molecular weight: 505.17 g/mol

Molecular formula: C10H14N5O13P3

InChI: InChI=1S/C10H14N5O13P3/c11-10-13-7-6(8(17)14-10)12-3-15(7)9-5(16)1-4(26-9)2-25-30(21,22)28-31(23,24)27-29(18,19)20/h1,3,5,9,16H,2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,17)/t5-,9-/m1/s1


3′,4′-Didehydro-3′-deoxyguanosine triphosphate is a metabolite of 3′,4′-Didehydro-3′-deoxyguanosine (DdhG). A related compound,  3′,4′-didehydro-3′-deoxycytidine triphosphate has been proven to have antiviral properties. It has the ability to prevent the replication of several viruses, including the Zika virus. This molecule is naturally produced in mammals through the dehydration of cytidine triphosphate (CTP), which is catalyzed by the enzyme viperin.



  • WO2020202142 A2 2020-10-08
  • WO2022038539 A2 2022-02-24

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