IUPAC Name: 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol
Other names: Plaquenil; Oxychlorochin; Hydroxychloroquine
Molecular weight: 335.88 g/mol
Hydroxychloroquine (HCQ), sold under the brand name Plaquenil among others, is a medication used to prevent and treat malaria in areas where malaria remains sensitive to chloroquine. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. Hydroxychloroquine is also being studied as an experimental treatment for coronavirus disease 2019 (COVID-19).
Hydroxychloroquine is in the antimalarial and 4-aminoquinoline families of medication and it was approved for medical use in the United States in 1955. It is one of the Essential Medicines in the World Health Organization’s List, the safest and most effective medicines needed in a health system, even though it has lots of common side effects (vomiting, headache, changes in vision, and muscle weakness).
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