Custom synthesis

We offer custom synthesis of previously reported molecules using described synthetic procedures as well as new, undescribed compounds through developing novel synthetic routes.

We deliver custom quantities from 1 mg to 100 g of final product.

Characterization will be performed using in house UHPLC-MS, HRMS and by NMR. We also offer synthesis optimization and upscaling specifically tailored to meet our customer’s needs.

Contract research

We offer expertise in synthetic and medicinal chemistry through collaborative efforts on a broad range of targets:
– Biologically active compounds
– Special reagents with unique properties
– Small libraries of compounds
– Long-term synthetic support (e.g. biochemical research)
– ADC linkers
– Nucleosides triphosphates and diphosphates
– Other sensitive and reactive tool compounds and probes
– Compounds targeted to meet our customers’ specific needs

Our employees have extensive experience in academic and private research labs and are accustomed to giving regular reports on advancements in the projects and to flexible adjustment of research targets and priorities.

Led by Passionate Experts
Kryštof Šigut

Kryštof is responsible for sales and finances.

Owner and a CEO of Santiago, a chemical and labware sourcing business

Contact: 776 750 591

Petr Slavík
Head of Chemistry

Petr is responsible for chemical part of company

Synthetic chemistry professional with 10+ years of experience in various fields of chemistry at international and Czech laboratories



Our story

Our laboratory is based on synergy between our expertise in chemical business and organic synthesis. We have more than 8 years of experience in providing custom chemicals to academic research laboratories and pharmaceutical companies around the globe. Our chemists have PhDs in chemistry from major Czech universities and over 10 years of experience in organic and medicinal chemistry at top scientific institutions.

Field of chemistry

In-house expertise
  • Heterocyclic chemistry
  • Palladium catalyzed reactions
  • Organometallic chemistry
  • Modification of enzyme substrates/inhibitors
  • ADC linkers
  • Triphosphates and diphosphates
  • Nucleos(t)ides
  • Fluorine chemistry
  • Photochemistry
  • Total synthesis of natural products
  • Prodrugs
  • Other sensitive and reactive tool compounds and probes

Laboratory equipment

Cutting-edge instrumentation for expedited research
  • HPLC-MS Agilent (60 MPa system with QQQ detection)
  • HPLC-DAD-MS Shimadzu (60 MPa system with full UV-vis and singleQ detection)
  • GC
  • MPLC ECOM (30 MPa preparative system)

The science of today is the technology of tomorrow

Our partners and customers


Drop us an email

We are Here

Radiova 1285/7
102 00 Praha 15 - Hostivar
Czech Republic

We are open

Mon – Fri 8am – 6pm CET
Sat – Sun – Closed

Drop us a line

We will respond as soon as possible, typically within 48 hours.

    The project “Preparation of ddh nucleoside markers of viral diseases and digitization of their production” was supported by the grant programme Czech Rise Up 3.0 founded by the European Union.