Characterisation
CAS: 1191237-69-0
IUPAC Name:(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
Other names: Nucleosid of Remdesivir; GS 441524
Molecular weight: 291.27 g/mol
Molecular formula: C12H13N5O4
Description
Nucleoside is an essential building block to the synthesis of Remdesivir triphosphate (1355149-45-9) and Remdesivir (1809249-37-3). Nukleosid derivate is used in the treatment of Feline infectious peritonitis (FIP). This fatal disease affects cats and is caused by a virus from a group of coronavirus. Remdesivir is nucleoside prodrug that metabolizes into GS-441524 which is phosphorylated to Remdesivir triphosphate. This phosphorus analog is mainly an active compound in the treatment of Ebola and COVID-19.
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