IUPAC Name: 5-(Ferrocene-1-yl-ethynyl)-2′-deoxycytidine triphosphate
Molecular weight: 675.2 g/mol; 741.2 g/mol (Na+ salt)
Storage: -20 °C, protect from light
5-(Ferrocene-1-yl-ethynyl)-2′-deoxycytidine triphosphate is a ferrocene labeled analog of natural cytidine triphosphate. Ferrocene is used as the gold standard for electrochemical labeling. Its conjugation at 5- position of cytidine triphosphate allows enzymatic incorporation of such analog in primer extension reactions and PCR. The compound might be used for electrochemical redox labeling of DNA, site-specific redox labeling, or in the development of highly sensitive genosensors.
5-(Ferrocene-1-yl-ethynyl)-2′-deoxycytidine triphosphate was synthesized and licensed at the IOCB Prague, lab of prof. Michal Hocek.
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