Entecavir triphosphate- CAS 336608-44-7

Entecavir triphosphate- CAS 336608-44-7

€3500 – €7000

Entecavir triphosphate- CAS 336608-44-7 is synthesized by Santiago Lab (Prague, Czech Republic). 

Purity (LC-MS)

min 95%

Package contents

Entecavir triphosphate triethylammonium salt

This compound is for research use only. We do not sell to patients.
SizeAvailabilityPriceQuantity
1 mg

In stock

 €3500
5 mg

In stock

 €7000

Entecavir triphosphate- CAS 336608-44-7

Characterisation

CAS: 336608-44-7

IUPAC Name:2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1H-purin-6-one tetrahydrogen triphosphate

Other names:

Molecular weight: 517.22 g/mol

Molecular formula: C12H18N5O12P3

InChI: InChI=1S/C12H18N5O12P3/c1-5-6(3-27-31(23,24)29-32(25,26)28-30(20,21)22)8(18)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)19/h4,6-8,18H,1-3H2,(H,23,24)(H,25,26)(H2,20,21,22)(H3,13,15,16,19)/t6-,7-,8-/m0/s1

Description

Entecavir triphosphate is a metabolite of Entacavit. Entecavir is a potent and selective hepatitis B virus reverse transcriptase inhibitor (EC50 = 3 nM); guanine analog. Inhibits hepatitis B virus replication in HepG2.2.15 cells. Displays selectively over HCMV, HSV-1, VZV, HIV and influenza (EC50 values are 15, 32, 30-60, >10 and >80 μM respectively). Orally bioavailable.

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