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Sulfo-Cyanine5 maleimide – CAS 2242791-82-6

Characterisation

CAS: 2242791-82-6

IUPAC Name: potassium 1-(6-((2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)amino)-6-oxohexyl)-3,3-dimethyl-2-((1E,3E)-5-((E)-1,3,3-trimethyl-5-sulfonatoindolin-2-ylidene)penta-1,3-dien-1-yl)-3H-indol-1-ium-5-sulfonate

Other names: Sulfo-Cyanine5 maleimide

Molecular weight: 803.0 g/mol

Molecular formula: C₃₈H₄₃KN₄O₉S₂

InChI: InChI=1S/C38H44N4O9S2.K/c1-37(2)28-24-26(52(46,47)48)15-17-30(28)40(5)32(37)12-8-6-9-13-33-38(3,4)29-25-27(53(49,50)51)16-18-31(29)41(33)22-11-7-10-14-34(43)39-21-23-42-35(44)19-20-36(42)45;/h6,8-9,12-13,15-20,24-25H,7,10-11,14,21-23H2,1-5H3,(H2-,39,43,46,47,48,49,50,51);/q;+1/p-1

Solubility: Water, DMF, DMSO

Excitation/absorption maximum: 646 nm

Emission maximum: 662 nm

Description

Introducing our hydrophilic and water-soluble sulfo-Cyanine5 maleimide, a superior analog to Cy5® maleimide. This product comes highly recommended for protein labeling applications, providing an excellent alternative to Cy5® maleimide, especially in the labeling of antibodies.

Achieve precise and efficient protein labeling with ease. The labeled proteins can be effortlessly separated from unreacted dye using various purification methods such as gel filtration, spin column purification, dialysis, electrophoresis, or chromatography. Elevate your protein labeling experiments with the reliability and convenience offered by our sulfo-Cyanine5 maleimide, ensuring optimal results and simplified purification processes.

References

• Shukla S, Wang C, Beiss V, Steinmetz NF. Antibody Response against Cowpea Mosaic Viral Nanoparticles Improves In Situ Vaccine Efficacy in Ovarian Cancer. ACS Nano. 2020;14(3):2994-3003. doi:10.1021/acsnano.9b07865

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