Archives

Reagent of the month – Amberlyst 15 ® resin Many synthetic applications use acidic catalysis, but having an extra compound in solution to serve as a catalyst, such as TsOH […]

Reagent of the month – November – Langlois reagent Trifluormehylation is an effective technique to increase drug candidate solubility and lipophilicity, and so strategies for adding the CF3 group are […]

Reagent of the month – DDQ and quinone-derived oxidants Reagents derived from p-quinone such as 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) or p-chloranil are used in a wide range of applications in organic synthesis […]

DMTMM in amide bond formation Amide bond formation is one the most widely occurring reactions in organic chemistry as well as in drug development. There are numerous ways to synthesize […]