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Contract research organization- Santiago lab
What does a contract research organization mean? A contract research organization (CRO) is a company that provides its solutions and expertise to other companies ranging from pharmaceutical, biotechnology or […]
Why are nucleoside triphosphates so important?
Triphosphates of nucleoside-based antiviral drugs Nucleoside analogues are the largest class of antiviral agents based on small molecules. Nowadays, they are the cornerstone of chemotherapy for several viral chronic infections, […]
Reagents of the month- April- Lawesson’s and Woollins’ reagents
Lawesson’s reagent Many biologically active substances contain a sulphur atom; however, it is usually not so easy to introduce sulphur into the molecule. Therefore, several thionation reagents were developed in […]
Custom synthesis – Santiago lab
How are custom synthesis projects done at Santiago? Custom synthesis can be beneficial in many ways. These days many researchers from various fields require specialised chemical reagents– starting building […]
Reagent of the month – March- DMTMM
DMTMM in amide bond formation Amide bond formation is one the most widely occurring reactions in organic chemistry as well as in drug development. There are numerous ways to synthesize […]
Paxlovid- history and mechanism of action
Paxlovid (Nirmatrelvir/Ritonavir) Paxlovid is a new potential drug for COVID-19 invented by Pfizer. Paxlovid is composed of two active ingredients, Nirmatrelvir and Ritonavir. Similarly, a mixture of Lopinavir and Ritonavir […]
Alaptide – history, biological activity and synthesis
Version in Czech is bellow the English version/ Verze v češtině se nachází pod anglickým textem Alaptide Many unique and interesting organic compounds were developed and synthesised by Czech and […]