Emtricitabine triphosphate – CAS 145819-92-7

7002500

Emtricitabine triphosphate is synthesised by Santiago Lab (Prague, Czech Republic)

We are providing Emtricitabine triphosphate in the form of Et3NH+ salt as a powder or water solution. All products are lyophilized and can easily sustain the shipment oversee.

Purity (LC-MS)

99%+ | Certificate of Analysis

Package contents

Emtricitabine triphosphate Et3NH+ salt

This compound is for research use only. We do not sell to patients.

We are sending Emtricitabine triphosphate in the form of Et3NH+ salt as a powder or water solution.

SizeAvailabilityPriceQuantity
1 mg

In stock

700
5 mg

In stock

1400
10 mg

In stock

2500
100mM/10μL

In stock

700
10mM/100μL

In stock

700

Characterisation

CAS: 145819-92-7, 2736455-57-3 (Et3NH+ salt)

IUPAC Name: Triphosphoric acid, P-​[[(2R,​5S)​-​5-​(4-​amino-​5-​fluoro-​2-​oxo-​1(2H)​-​pyrimidinyl)​-​1,​3-​oxathiolan-​2-​yl]​methyl] ester (Et3NH+ salt)

Other names: Emtricitabine triphosphate, Emtricitabine TP

Molecular weight: 487.19 g/mol, 

Molecular formula: C8 H13 F N3 O12 P3 S

Storage: -20 °C, protect from light, stored under argon

We are providing Emtricitabine triphosphate in the form of Et3NH+ salt as a powder or water solution.

Description

Emtricitabine triphosphate is synthesised by Santiago Lab (Prague, Czech Republic).

Emtricitabine (commonly called FTC, systematic name 2′,3′-dideoxy-5-fluoro-3′-thiacytidine), with trade name Emtriva (formerly Coviracil), is a nucleoside reverse-transcriptase inhibitor (NRTI) for the prevention and treatment of HIV infection in adults and children.

Emtricitabine is also marketed in a fixed-dose combination with tenofovir disoproxil (Viread) under the brand name Truvada, and with tenofovir alafenamide (Vemlidy) under the brand name Descovy.

A fixed-dose triple combination of emtricitabine, tenofovir and efavirenz (Sustiva, marketed by Bristol-Myers Squibb) was approved by the U.S. Food and Drug Administration (FDA) on July 12, 2006, under the brand name Atripla.

Chemicals are distributed worldwide

Buy Emtricitabine triphosphate now, get your order in 48 hours
  • Shipping through DHL in 48 hours. We can also arrange shipping on dry ice.
  • All compounds are safely and rigorously packed
Payment
  • We are sending the invoice the same day as the shipment
  • We can modify the invoice for the academic institution so that the order can be paid from grants
References

References
1. US 5814639, Liotta DC, Schinazi RF, Choi WB, "Method for the synthesis, compositions and use of 2'-deoxy-5-fluoro-3'-thiacytidine and related compounds", issued 29 September 1998
2. xenius A, Price DA, Günthard HF, Dawson SJ, Fagard C, Perrin L, et al. (October 2002). "Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection". Proceedings of the National Academy of Sciences of the United States of America. 99 (21): 13747–52. Bibcode:2002PNAS…9913747O. doi:10.1073/pnas.202372199

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