Telbivudine triphosphate – CAS 152502-95-9


Telbivudine triphosphate is synthesised by Santiago Lab (Prague, Czech Republic).

We are providing Telbivudine triphosphate in the form of Et3NH+ salt. All products are lyophilized and can easily sustain the shipment oversee.

Purity (LC-MS)

99%+ | Certificate of Analysis

Package contents

Telbivudine triphosphate Et3NH+ salt

This compound is for research use only. We do not sell to patients.

We are sending Telbivudine triphosphate in the form of Et3NH+ salt.

1 mg

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5 mg

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10 mg

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CAS: 152502-95-9, 207128-24-3 (Et3NH+ salt)

IUPAC Name: 1-​[2-​deoxy-​5-​O-​[hydroxy[[hydroxy(ph​osphonooxy)​phosphinyl]​oxy]​phosphinyl]​-​β-​L-​erythro-​pentofuranosyl]​-​5-​methyl-2,​4(1H,​3H)​-​pyrimidinedione

Other names: Telbivudine triphosphate, Telbivudine TP

Molecular weight: 428.17 g/mol, 

Molecular formula: C10 H17 N2 O14 P3

Storage: -20 °C, protect from light, stored under argon

We are providing Telbivudine triphosphate in the form of Et3NH+ salt.


Telbivudine triphosphate is synthesised by Santiago Lab (Prague, Czech Republic).

Telbivudine is an antiviral drug used in the treatment of hepatitis B infection. It is marketed by Swiss pharmaceutical company Novartis under the trade names Sebivo (European Union) and Tyzeka (United States). Clinical trials have shown it to be significantly more effective than lamivudine or adefovir, and less likely to cause resistance. However, HBV signature resistance mutation M204I (a change from methionine to isoleucine at position 204 in the reverse transcriptase domain of the hepatitis B polymerase) or L180M+M204V have been associated with Telbivudine resistance.

Telbivudine is a synthetic thymidine β-L-nucleoside analogue; it is the L-isomer of thymidine. Telbivudine impairs hepatitis B virus (HBV) DNA replication by leading to chain termination. It differs from the natural nucleotide only with respect to the location of the sugar and base moieties, taking on a levorotatory configuration versus a dextrorotatory configuration as do the natural deoxynucleosides

Chemicals are distributed worldwide

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1. Lai CL, Leung N, Teo EK, et al. (2005). "A 1-year trial of telbivudine, lamivudine, and the combination in patients with hepatitis B e antigen-positive chronic hepatitis B". Gastroenterology. 129 (2): 528–36. doi:10.1016/j.gastro.2005.05.053. PMID 16083710.
2. Lai CL, Gane E, Liaw YF, et al. (2007). "Telbivudine versus lamivudine in patients with chronic hepatitis B". N Engl J Med. 357 (25): 2576–88. doi:10.1056/NEJMoa066422. hdl:10722/57525.

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