Reagent of the month – CBS oxazaborolidine

February 16, 2023|Uncategorized | 3 Min Read

Reagent of the month – CBS oxazaborolidine The Corey-Bakshi-Shibata (CBS) catalyst is an organocatalyst that is used in asymmetric ketone reductions (Corey-Itsuno reduction). The structure of the CBS oxazaborolidine catalyst […]

Read More

Introduction to antibody-drug conjugates (ADCs)

November 22, 2022|Uncategorized | 4 Min Read

Introduction to antibody-drug conjugates (ADCs) The selectivity of therapeutic drugs to cancer cells over healthy tissue is one of the most challenging difficulties in cancer treatment. The employment of sophisticated […]

Read More

Why are nucleoside triphosphates so important?

May 9, 2022|Uncategorized | 4 Min Read

Triphosphates of nucleoside-based antiviral drugs Nucleoside analogues are the largest class of antiviral agents based on small molecules. Nowadays, they are the cornerstone of chemotherapy for several viral chronic infections, […]

Read More

Reagents of the month- April- Lawesson’s and Woollins’ reagents

April 19, 2022|Uncategorized | 3 Min Read

Lawesson’s reagent Many biologically active substances contain a sulphur atom; however, it is usually not so easy to introduce sulphur into the molecule. Therefore, several thionation reagents were developed in […]

Read More

Paxlovid- history and mechanism of action

February 23, 2022|Uncategorized | 3 Min Read

Paxlovid (Nirmatrelvir/Ritonavir) Paxlovid is a new potential drug for COVID-19 invented by Pfizer. Paxlovid is composed of two active ingredients, Nirmatrelvir and Ritonavir. Similarly, a mixture of Lopinavir and Ritonavir […]

Read More


November 19, 2021|Antivirals, Nucleosides, Triphosphates, Uncategorized | 3 Min Read
Molnupiravir is a new potential drug against the SARS-CoV-2 infectious virus.   To this date, all medications against SARS-CoV-2 are administered only by infusion and only in severe disease cases [...]
Read More