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Why are nucleoside triphosphates so important?

May 9, 2022|Uncategorized | 4 Min Read

Triphosphates of nucleoside-based antiviral drugs Nucleoside analogues are the largest class of antiviral agents based on small molecules. Nowadays, they are the cornerstone of chemotherapy for several viral chronic infections, […]

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Reagents of the month- April- Lawesson’s and Woollins’ reagents

April 19, 2022|Uncategorized | 3 Min Read

Lawesson’s reagent Many biologically active substances contain a sulphur atom; however, it is usually not so easy to introduce sulphur into the molecule. Therefore, several thionation reagents were developed in […]

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Paxlovid- history and mechanism of action

February 23, 2022|Uncategorized | 3 Min Read

Paxlovid (Nirmatrelvir/Ritonavir) Paxlovid is a new potential drug for COVID-19 invented by Pfizer. Paxlovid is composed of two active ingredients, Nirmatrelvir and Ritonavir. Similarly, a mixture of Lopinavir and Ritonavir […]

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Molnupiravir

November 19, 2021|Antivirals, Nucleosides, Triphosphates, Uncategorized | 3 Min Read
Molnupiravir is a new potential drug against the SARS-CoV-2 infectious virus.   To this date, all medications against SARS-CoV-2 are administered only by infusion and only in severe disease cases [...]
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